12th Apr 10
Source: Family & Life
Doctors carried out groundbreaking surgery to rebuild the windpipe of a 10-year-old British boy with his own stem cells. If the procedure succeeds, they say it could bring a revolution in regenerative medicine. The operation, which lasted almost nine hours, took place at London’s Great Ormond Street Children’s Hospital last month.
Doctors injected stem cells from the boy’s bone marrow into the fibrous collagen “scaffold” of a donor trachea (windpipe). Then they implanted the organ, which had first been stripped of its own cells, into the boy.
Over the next month, doctors expect the stem cells to start transforming themselves into internal and external tracheal cells. The boy, whose identity is a secret, is reportedly doing well and breathing normally. Because they are derived from his own tissue, there is no danger of the newly grown cells triggering an immune response. In an ordinary transplant, doctors would suppress the patient’s immune system with drugs to prevent rejection of the organ.
The new procedure was a big step forward from the pioneering surgery done in Spain two years ago on 30-year-old mother of two Claudia Castillo, the first person ever to receive a transplant organ created from stem cells. She received a section of tracheal airway rebuilt from stem cells, but using a much more complex and costly process.
Prof Martin Birchall, head of translational regenerative medicine at University College London, said, “This procedure is different in a number of ways, and we believe it’s a real milestone”. The Irish Times. March 23.
Showing posts with label adult stem cell research. Show all posts
Showing posts with label adult stem cell research. Show all posts
Tuesday, April 13, 2010
Monday, March 15, 2010
Ireland and Stem Cell Research
Pro Life Campaign and Family and Life host Stem Cell Experts in Dublin
Source: Pro Life Campaign
In an important visit to Ireland, co-hosted by the Pro-Life Campaign and Family and Life, Professor Robert George of Princeton University and Professor William Hurlbut of Stanford University were in Dublin last week meeting with politicians, academics and pro-life supporters to discuss the need for protection of human life at its earliest stages of development and to make the case for ethical stem cell research that does not involve the destruction of human embryos
Professors George and Hurlbut met with members of the Dáil and Seanad and addressed academics and students in the Royal College of Surgeons, DCU and UCD. On Friday evening, they addressed several hundred pro-life supporters in the Davenport Hotel where they outlined to the audience the scientific and philosophical arguments underpinning a respect for human lives from the moment of fertilisation. Professor William Hurlbut , a professor in Human Biology at Stanford University explained the application and potential of adult stem cells in particular the procedure by which pluripotent stem cells (adult stem cells with the capacity to differentiate into different germ layers) can be used in a way that emulates embryonic stem cells. The significance of this is that no embryonic human being need be used for research and at present non-controversial adult stem cell research is having more success at treating diseases. Professor Robert George who is McCormick Professor of Jurisprudence at Princeton University picked through the popular arguments used to de-humanise the embryonic human being and explained why the embryonic human life is deserving of full protection of society and the law. The event was chaired by Senator Rónán Mullen.
The three-day visit of the Professors to Ireland was a great success and Professor George was interviewed on Today with Pat Kenny on the morning of Friday 5th March.
Source: Pro Life Campaign
In an important visit to Ireland, co-hosted by the Pro-Life Campaign and Family and Life, Professor Robert George of Princeton University and Professor William Hurlbut of Stanford University were in Dublin last week meeting with politicians, academics and pro-life supporters to discuss the need for protection of human life at its earliest stages of development and to make the case for ethical stem cell research that does not involve the destruction of human embryos
Professors George and Hurlbut met with members of the Dáil and Seanad and addressed academics and students in the Royal College of Surgeons, DCU and UCD. On Friday evening, they addressed several hundred pro-life supporters in the Davenport Hotel where they outlined to the audience the scientific and philosophical arguments underpinning a respect for human lives from the moment of fertilisation. Professor William Hurlbut , a professor in Human Biology at Stanford University explained the application and potential of adult stem cells in particular the procedure by which pluripotent stem cells (adult stem cells with the capacity to differentiate into different germ layers) can be used in a way that emulates embryonic stem cells. The significance of this is that no embryonic human being need be used for research and at present non-controversial adult stem cell research is having more success at treating diseases. Professor Robert George who is McCormick Professor of Jurisprudence at Princeton University picked through the popular arguments used to de-humanise the embryonic human being and explained why the embryonic human life is deserving of full protection of society and the law. The event was chaired by Senator Rónán Mullen.
The three-day visit of the Professors to Ireland was a great success and Professor George was interviewed on Today with Pat Kenny on the morning of Friday 5th March.
Monday, February 15, 2010
Minister Harney should learn from California's experience - Money spent on embryonic stem cell research is money wasted.
Source : Pro Life Campaign
There are three billion reasons not to allow the Supreme Court ruling in R v. R to be used as a cover to legalise research here involving human embryo destruction.
In 2004, Californian taxpayers agreed to fund embryo stem cell research to the tune of $3 billion in the hope of finding cures for chronic diseases and disabilities. But since then, not a single breakthrough has taken place.
Now the Los Angeles-based Investor’s Business Daily magazine is reporting that the California Institute for Regenerative Medicine set up to administer the $3b has started diverting the funds earmarked for embryo research into the ethically non-controversial adult stem cell research.
In the wake of the Supreme Court ruling in Ireland stripping Constitutional protection from human embryos in vitro, the latest developments from California take on a significant added meaning. With her experience in other ministries, Minister Harney is in a position to appreciate the economic as well as the medical knock-on effects of making Ireland an international centre of excellence for the ethically non-controversial adult stem cell research.
Minister For Health Mary Harney may well try to rush through a regulatory framework allowing embryo destruction to meet the interests of the IVF and embryo research industries. She is on record as saying she has asked her officials to prepare heads of legislation and it is expected the proposed legislation will follow the recommendations of the Commission on Assisted Human Reproduction’s 2005 Report. The membership of this Commission was outrageously biased in favour of allowing embryo destruction – they voted 24 to 1 for it, only Professor Gerard Whyte of TCD dissenting, click here to see his closely reasoned dissent.
Clearly the recommendations of such a biased body are not a fitting basis for legislation in a democracy, all the more so when such run contrary to the balance of opinion among the general public, measured time and again in professionally carried out opinion polls every year since the biased Report was issued, which have found a majority of around 70% support the Dáil passing legislation protecting embryos against destruction in clinics and laboratories.
But Minister Mary Harney may also defend legislation allowing the destruction of human embryos in vitro on the grounds that embryo destruction is needed to provide embryonic stem cells for research to produce new medical treatments.
This argument, however, has turned out to be as flawed as an appeal to the biased Commission on Assisted Human Reproduction Report. For years we have been bombarded by propaganda saying killing human embryos has to be allowed so research using stem cells got by that way may lead to new medical treatments. But now we are finding out this simply ain’t so. It’s been all promise, but no product.
In 2004 California approved Proposition 71, a ballot measure allowing the State to borrow US $3 billion to fund stem cell research using stem cells obtained by destroying human embryos. The money was to be used, its proponents said, to develop new treatments based on embryonic stem cell research. The State agency set up to manage this was the California Institute for Regenerative Medicine.
On 12th January this year, the Los Angeles-based Investor’s Business Daily magazine reported that because the research using stem cells obtained by killing human embryos has not produced any breakthroughs in medical treatments, the California Institute for Regenerative Medicine ‘is diverting funds’ to the research approach that ‘has produced actual therapies and treatments : adult stem cell research.’
Adult stem cell research, the Investor’s Business Daily comments, ‘not only has treated real people with real results it also does not come with the moral baggage embryonic stem cell research does.
It goes on to comment that advocates of embryonic stem cell research have engaged in a sort of three card trick:
To us this is a classic bait and switch, an attempt to snatch success from the jaws of failure and take credit for discoveries and advances achieved by research (which) Proposition 71 supporters once cavalierly dismissed. We have noted how over the years that when funding was needed, the phrase “embryonic stem cells” was used. When actual progress was discussed, the word “embryonic” was dropped because embryonic stem cell research never got out of the lab. Click here to read the Investor's Business Daily article in full.
So if Minister Mary Harney or the voices of the IVF and embryo research industries in Ireland start arguing that we need a regulatory framework allowing embryo destruction in order to open the door for research promising breakthroughs in medical treatment, the answer is we already know what lies down that path. California three US $ 3 billion at it and there were no results and now the agency set up to get results is diverting the money into adult stem cell research so it will have some results to show.
The real message of the Californian experience, then is that Ireland has a golden opportunity to put substantial resources into adult stem cell research to make Ireland an international centre of excellence in this field of research which is actually producing the goods.
There are three billion reasons not to allow the Supreme Court ruling in R v. R to be used as a cover to legalise research here involving human embryo destruction.
In 2004, Californian taxpayers agreed to fund embryo stem cell research to the tune of $3 billion in the hope of finding cures for chronic diseases and disabilities. But since then, not a single breakthrough has taken place.
Now the Los Angeles-based Investor’s Business Daily magazine is reporting that the California Institute for Regenerative Medicine set up to administer the $3b has started diverting the funds earmarked for embryo research into the ethically non-controversial adult stem cell research.
In the wake of the Supreme Court ruling in Ireland stripping Constitutional protection from human embryos in vitro, the latest developments from California take on a significant added meaning. With her experience in other ministries, Minister Harney is in a position to appreciate the economic as well as the medical knock-on effects of making Ireland an international centre of excellence for the ethically non-controversial adult stem cell research.
Minister For Health Mary Harney may well try to rush through a regulatory framework allowing embryo destruction to meet the interests of the IVF and embryo research industries. She is on record as saying she has asked her officials to prepare heads of legislation and it is expected the proposed legislation will follow the recommendations of the Commission on Assisted Human Reproduction’s 2005 Report. The membership of this Commission was outrageously biased in favour of allowing embryo destruction – they voted 24 to 1 for it, only Professor Gerard Whyte of TCD dissenting, click here to see his closely reasoned dissent.
Clearly the recommendations of such a biased body are not a fitting basis for legislation in a democracy, all the more so when such run contrary to the balance of opinion among the general public, measured time and again in professionally carried out opinion polls every year since the biased Report was issued, which have found a majority of around 70% support the Dáil passing legislation protecting embryos against destruction in clinics and laboratories.
But Minister Mary Harney may also defend legislation allowing the destruction of human embryos in vitro on the grounds that embryo destruction is needed to provide embryonic stem cells for research to produce new medical treatments.
This argument, however, has turned out to be as flawed as an appeal to the biased Commission on Assisted Human Reproduction Report. For years we have been bombarded by propaganda saying killing human embryos has to be allowed so research using stem cells got by that way may lead to new medical treatments. But now we are finding out this simply ain’t so. It’s been all promise, but no product.
In 2004 California approved Proposition 71, a ballot measure allowing the State to borrow US $3 billion to fund stem cell research using stem cells obtained by destroying human embryos. The money was to be used, its proponents said, to develop new treatments based on embryonic stem cell research. The State agency set up to manage this was the California Institute for Regenerative Medicine.
On 12th January this year, the Los Angeles-based Investor’s Business Daily magazine reported that because the research using stem cells obtained by killing human embryos has not produced any breakthroughs in medical treatments, the California Institute for Regenerative Medicine ‘is diverting funds’ to the research approach that ‘has produced actual therapies and treatments : adult stem cell research.’
Adult stem cell research, the Investor’s Business Daily comments, ‘not only has treated real people with real results it also does not come with the moral baggage embryonic stem cell research does.
It goes on to comment that advocates of embryonic stem cell research have engaged in a sort of three card trick:
To us this is a classic bait and switch, an attempt to snatch success from the jaws of failure and take credit for discoveries and advances achieved by research (which) Proposition 71 supporters once cavalierly dismissed. We have noted how over the years that when funding was needed, the phrase “embryonic stem cells” was used. When actual progress was discussed, the word “embryonic” was dropped because embryonic stem cell research never got out of the lab. Click here to read the Investor's Business Daily article in full.
So if Minister Mary Harney or the voices of the IVF and embryo research industries in Ireland start arguing that we need a regulatory framework allowing embryo destruction in order to open the door for research promising breakthroughs in medical treatment, the answer is we already know what lies down that path. California three US $ 3 billion at it and there were no results and now the agency set up to get results is diverting the money into adult stem cell research so it will have some results to show.
The real message of the Californian experience, then is that Ireland has a golden opportunity to put substantial resources into adult stem cell research to make Ireland an international centre of excellence in this field of research which is actually producing the goods.
Wednesday, February 10, 2010
Stem Cell Research in Ireland
R -v- R Supreme Court decision regrettable but creates an opportunity to unite ethics and science in favour of a win-win solution
Those who believe that human life should be protected at all stages will be disappointed with the Supreme Court decision in the R v. R frozen embryos case that was made on the 15th of December last. The Supreme Court ruled that Article 40.3.3 of the Constitution does not afford protection to the human embryo prior to implantation.
The Government must introduce legislation to protect human life at its earliest stages of development. The human embryo is not potential life - it is human life with potential. Each one of us passed through this early stage of life on our way to birth. The very basis of democracy is respect for the equal dignity and worth of every human being under the law. Our first and most important human right is the right to life.
The fact that the Supreme Court ruled that the human embryo does not enjoy protection under Article 40.3.3 of the Constitution in no way impedes the Government from introducing legislation to protect early human life. There is precedent for such legislation in countries like Italy and Germany where protections for the human embryo were introduced despite there being no explicit Constitutional protection in those countries for human life at its fragile beginnings.
The Supreme Court decision marks the beginning not the end of the debate on how best to proceed. The totally unrepresentative composition of the Commission on Assisted Human Reproduction (CAHR), which voted 24 to 1 in favour of destructive embryo research, is certainly not the basis for any legislation. Before legislation is proposed, the Government must address the glaring imbalance to date in the consultative process. We need legislation to protect the human embryo not the continued outsourcing of decision making to unaccountable quangos or to some 'regulatory body'.
We must not, as a society, pass over this opportunity to unite ethics and science in a win-win solution that could make Ireland a centre of excellence for adult stem cell research, which is ethically sound and scientifically very promising.The unfolding debate is not about those in favour of research pitched in ideological battle against those opposed to scientific advances. Pro-life supporters are just as enthusiastic about the promise of finding treatments for infertility and cures for diseases, but strongly believe this can be achieved without recourse to the taking of human life.
Those who believe that human life should be protected at all stages will be disappointed with the Supreme Court decision in the R v. R frozen embryos case that was made on the 15th of December last. The Supreme Court ruled that Article 40.3.3 of the Constitution does not afford protection to the human embryo prior to implantation.
The Government must introduce legislation to protect human life at its earliest stages of development. The human embryo is not potential life - it is human life with potential. Each one of us passed through this early stage of life on our way to birth. The very basis of democracy is respect for the equal dignity and worth of every human being under the law. Our first and most important human right is the right to life.
The fact that the Supreme Court ruled that the human embryo does not enjoy protection under Article 40.3.3 of the Constitution in no way impedes the Government from introducing legislation to protect early human life. There is precedent for such legislation in countries like Italy and Germany where protections for the human embryo were introduced despite there being no explicit Constitutional protection in those countries for human life at its fragile beginnings.
The Supreme Court decision marks the beginning not the end of the debate on how best to proceed. The totally unrepresentative composition of the Commission on Assisted Human Reproduction (CAHR), which voted 24 to 1 in favour of destructive embryo research, is certainly not the basis for any legislation. Before legislation is proposed, the Government must address the glaring imbalance to date in the consultative process. We need legislation to protect the human embryo not the continued outsourcing of decision making to unaccountable quangos or to some 'regulatory body'.
We must not, as a society, pass over this opportunity to unite ethics and science in a win-win solution that could make Ireland a centre of excellence for adult stem cell research, which is ethically sound and scientifically very promising.The unfolding debate is not about those in favour of research pitched in ideological battle against those opposed to scientific advances. Pro-life supporters are just as enthusiastic about the promise of finding treatments for infertility and cures for diseases, but strongly believe this can be achieved without recourse to the taking of human life.
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